Murat Demirtaş

Disruption of Striatal Intrinsic Ignition in Huntington's Disease: an In-Silico Perturbational Approach to Emulate Disease Progression and Recovery

This study uses computational modeling to simulate functional connectivity changes in Huntington's disease and assess recovery potential by perturbing striatal activity.

Large Scale Functional and Effective Connectivity Alterations cross the Huntington's Disease Integrated Staging System

This study uses fMRI to assess functional and effective connectivity changes across HD-ISS stages, finding attenuated connectivity in early stages and sensitivity to motion.

Personalized circuit modeling captures variation in cortical functional connectivity

The paper develops a biophysically-based circuit model to capture individual variation in cortical functional connectivity using resting-state fMRI data from the Human Connectome Project.

Design of effective personalised perturbation strategies for enhancing cognitive intervention in Alzheimer's disease

The paper uses computational modeling to identify key brain regions for personalized neurostimulation strategies to improve cognitive interventions in Alzheimer's disease.

Transcriptomics-informed large-scale cortical model captures topography of pharmacological neuroimaging effects of LSD

The paper integrates transcriptomics with large-scale cortical modeling to simulate LSD's effects on brain function, revealing serotonin-2A receptor-mediated changes in cortical connectivity.

Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics

The paper develops a dynamical circuit model of human cortex incorporating hierarchical heterogeneity to better explain large-scale neural dynamics and functional connectivity.

Distinct Modes of Functional Connectivity induced by Movie-Watching

This study identifies a distinct functional connectivity mode during movie-watching that reflects individual differences and is stable over time.

Hierarchy of transcriptomic specialization across human cortex captured by myelin map topography

The paper uses MRI-derived myelin maps to identify hierarchical transcriptomic gradients in human cortex, linking anatomical hierarchy to gene expression patterns.

Exploring Anti-correlated Resting State BOLD Signals Through Dynamic Functional Connectivity and Whole-brain Computational Modeling

The paper analyzes anti-correlated resting-state BOLD signals using dynamic functional connectivity and whole-brain modeling, finding hemodynamic response function drives fluctuations in connectivity and anti-correlations.