Author

Andrew Wood

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Neuroscience· 2 Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Approach:graph neural network· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Cristina SampaioiD· 2 shared Dorian PustinaiD· 2 shared Gustavo DecoiD· 2 shared Jakub VohryzekiD· 2 shared Murat DemirtaşiD· 2 shared Aaron McDaid· 1 shared Anna MurrayiD· 1 shared Anping Guo· 1 shared

Activity by Year

2016-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Cristina SampaioORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Disruption of Striatal Intrinsic Ignition in Huntington's Disease: an In-Silico Perturbational Approach to Emulate Disease Progression and Recovery

Murat Demirtaş, Dorian Pustina, Andrew Wood, Cristina Sampaio, Jakub Vohryzek, Gustavo Deco

This study uses computational modeling to simulate functional connectivity changes in Huntington's disease and assess recovery potential by perturbing striatal activity.

bioRxiv · Dec 10, 2025 · PreprintNeuroscience

Large Scale Functional and Effective Connectivity Alterations cross the Huntington's Disease Integrated Staging System

Murat Demirtaş, Dorian Pustina, Andrew Wood, Cristina Sampaio, Jakub Vohryzek, Gustavo Deco

This study uses fMRI to assess functional and effective connectivity changes across HD-ISS stages, finding attenuated connectivity in early stages and sensitivity to motion.

bioRxiv · Dec 2, 2025Neuroscience

Chemically Induced Nuclear Pore Complex Protein Degradation via E3 Ligase TRIM21

Xiaomei Li, Qingyang Wang, Anping Guo, Yaping Qiu, Qiuxia Chen, You Li, Lanjun Zhang, Yaxin Guo, Xiaoyun Meng, Shiqian Li, Guizhi Liu, Liyun Zhang, Jian Liu, Xianyang Li, Longying Cai, , Dengfeng Dou

This study identifies small-molecule ligands for TRIM21, an E3 ligase, demonstrating their ability to degrade nuclear pore complex proteins and induce cell death in cancer cells.

ACS Chemical Biology · Apr 18, 2025Peer-reviewedCell Biology

Improved And Optimized Drug Repurposing For The SARS-CoV-2 Pandemic

Sarel Cohen, Moshik Hershcovitch, Martin Taraz, Otto Kißig, Davis Issac, Andrew Wood, Daniel Waddington, Peter S. Chin, Tobias Friedrich

The paper improves drug repurposing for SARS-CoV-2 by enhancing a graph neural network model, generating candidate drugs, and optimizing computational efficiency.

PLoS ONE · Mar 16, 2023Peer-reviewedBioinformatics

Psip1/p52 regulates distal Hoxa genes through activation of lncRNA Hottip

Madapura M Pradeepa, Gillian AG Taylor, Graeme R Grimes, Andrew Wood, Wendy Bickmore

The paper shows Psip1/p52 regulates lncRNA Hottip, which in turn activates distal Hoxa genes in mouse embryonic stem cells.

PLOS Genetics · Apr 6, 2017Peer-reviewedGenetics

Quantifying the extent to which index event biases influence large genetic association studies

Hanieh Yaghootkar, Michael Bancks, Sam Jones, Aaron McDaid, Robin Beaumont, Louise Donnelly, Andrew Wood, Archie Campbell, Jessica Tyrrell, Lynne Hocking, Marcus Tuke, Katherine Ruth, Ewan Pearson, Anna Murray, Rachel Freathy, , Zoltan Kutalik

This study quantifies index event bias in large genetic association studies and finds it can explain some associations between disease risk alleles and BMI.

bioRxiv · Sep 12, 2016Genetics