Yoichi Shinkai

The paper investigates mitochondrial translation termination, recycling, and quality control mechanisms using Ribo-Seq and Disome-Seq, revealing roles of release factors and rescue mechanisms.

This study introduces H3K9 methylation and HP1 into budding yeast to examine their role in heterochromatin formation, finding they do not significantly alter chromatin structure or transcription.

The paper investigates how H3K9 and H3K27 methylation regulate CTCF binding and 3D genome structure in mouse cells, showing that their loss disrupts chromatin organization and gene expression.

This study shows that Resf1 is essential for placental development and trophoblast cell-specific heterochromatin configuration in mice, with loss of Resf1 leading to retroelement upregulation and developmental defects.

The paper investigates how H3K27me3 and the PRC1-H2AK119ub pathway work together to maintain heterochromatin structure after H3K9 methylation loss in mammalian cells.

The paper investigates the effect of Trichostatin A on nuclear compartments in cells lacking H3K9me, H3K27me3, and uH2A, finding minimal impact on compartment structure despite increased H3K27ac levels.

This study shows that OVGP1, an oviductal humoral factor, is essential for female fertility and early embryonic development in golden hamsters.

This study identifies METTL18 as a histidine methyltransferase that modifies RPL3, slowing ribosome translocation on tyrosine codons to aid protein folding and prevent aggregation.

The paper investigates how transcriptional states and KRAB-ZFPs regulate DNA methylation of retroelements in human male germ cells, revealing inter-individual epigenetic variation in sperm.

The paper investigates the role of H3K9me2 in 3D genome organization by analyzing its distribution, transcriptome, and chromatin structure in mouse embryonic stem cells with altered H3K9 methyltransferase activity.