Author

Aishwarya Swain

Pondicherry UniversityORCID 0000-0002-6052-4848Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Archana PaniD· 2 shared Biji ChatterjeeiD· 2 shared Bramanandam ManavathiiD· 2 shared Chandrashekhar G. JoshiiD· 2 shared Jagadeesha PoyyaiD· 2 shared Kirankumar NallaiD· 2 shared Santosh Raja KanadeiD· 2 shared Krishna Ghosh· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Archana PanORCID

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2 papers

Recent·Most cited

Ellagic acid: a potential inhibitor of enhancer of zeste homolog-2 and protein arginine methyltransferase-5

Kirankumar Nalla, Biji Chatterjee, Jagadeesha Poyya, Aishwarya Swain, Krishna Ghosh, Archana Pan, Chandrashekhar G. Joshi, Bramanandam Manavathi, Santosh Raja Kanade

This study identifies ellagic acid as an inhibitor of EZH2 and PRMT5:MEP50, showing reduced histone modifications and tumor growth in mouse models.

Cancer Genetics · Sep 2, 2025Peer-reviewedCancer Biology

Epigallocatechin-3-gallate inhibit the protein arginine methyltransferase 5 and Enhancer of Zeste homolog 2 in breast cancer both in vitro and in vivo

Kirankumar Nalla, Biji Chatterjee, Jagadeesha Poyya, Aishwarya Swain, Krishna Kanta Ghosh, Archana Pan, Chandrashekhar G. Joshi, Bramanandam Manavathi, Santosh Raja Kanade

This study shows that EGCG inhibits PRMT5 and EZH2 in breast cancer cells and xenografts, reducing histone repressive marks and inducing apoptosis and autophagy.

Archives of Biochemistry and Biophysics · Nov 22, 2024Peer-reviewedCancer Biology