Author

Malte L. Pinckert

University of CambridgeORCID 0000-0002-6072-5949Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:software / tool· 1 Research Focus:variant calling· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alex Alderton· 1 shared Aminu S Jahun· 1 shared Andrew Lim· 1 shared Andrew R J Lawson· 1 shared Anna Yakovleva· 1 shared Charlotte J. HouldcroftiD· 1 shared Cordelia Langford· 1 shared Cristina Ariani· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Alex Alderton

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2 papers

Recent·Most cited

comrades-OO: An Object-Oriented R Package for Comprehensive Analysis of RNA Structure Generated using RNA crosslinking experiments

Jonathan L. Price, Omer Ziv, Malte L. Pinckert, Andrew Lim, Eric Alexander Miska

comradesOO is an R package for analyzing RNA structure data from COMRADES experiments, providing tools for processing, clustering, and comparing RNA structures and interactions.

Bioinformatics · Mar 29, 2024Peer-reviewedBioinformatics

Patterns of within-host genetic diversity in SARS-CoV-2

Gerry Tonkin-Hill, Iñigo Martincorena, Roberto Amato, Andrew R J Lawson, Moritz Gerstung, Ian Johnston, David K Jackson, Naomi R Park, Stefanie V Lensing, Michael A Quail, Sónia Gonçalves, Cristina Ariani, Michael Spencer Chapman, William L Hamilton, Luke W Meredith, , Dominic Kwiatkowski

This study analyzes within-host genetic diversity in 1,181 SARS-CoV-2 samples, finding high mutation rates, strand asymmetries, and purifying selection, with implications for transmission chain reconstruction.

eLife · Aug 13, 2021Peer-reviewedGenomics