Omics-Based Interaction Framework - a systems model to reveal molecular drivers of synergy
Jezreel Pantaleón García, Vikram V. Kulkarni, Tanner C. Reese, Shradha Wali, Saima J. Wase, Jiexin Zhang, Ratnakar Singh, Mauricio S. Caetano, Seyed Javad Moghaddam, Faye M. Johnson, Jing Wang, Yongxing Wang, Scott E. Evans
The paper introduces OBIF, a systems model that identifies molecular drivers of synergy by integrating statistical and biological interactions from omics data.
bioRxiv · Apr 16, 2020 · PreprintSystems Biology