Author

Faye M. Johnson

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-2862-4160Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jeffery N. MyersiD· 3 shared Abdullah A. OsmaniD· 2 shared Curtis R. PickeringiD· 2 shared Jiexin ZhangiD· 2 shared Jing WangiD· 2 shared Kazi Mokim AhmediD· 2 shared Kunal RaiiD· 2 shared Mitchell J. FrederickiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Jeffery N. MyersORCID

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4 papers

Recent·Most cited

Chromatin Landscape of Cancer Cell Lines Identifies Enhancer Subtypes

Mayinuer Maitituoheti, Emre Arslan, Ayush T. Raman, Christopher J. Terranova, Zhiyi Liu, Elias Orouji, Sanjana Srinivasan, Veena Kochat, Ming Tang, Samirkumar B. Amin, Jonathan E. Schulz, Neha S. Samant, Anand Singh, Emmanuel Martínez-Ledesma, Sharmistha Sarkar, , Kunal Rai

The paper identifies enhancer subtypes in cancer cell lines and tumors, revealing distinct epigenetic patterns and potential therapeutic targets.

bioRxiv · Aug 4, 2026 · PreprintCancer Biology

NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck Cancer

Chenfei Huang, Shhyam Moorthy, Qiuli Li, Kazi Mokim Ahmed, Kalil Saab, Defeng Deng, Jiping Wang, Xiayu Rao, Jiexin Zhang, Yuanxin Xi, Jing Wang, Zhiyi Liu, Noriaki Tanaka, David A. Wheeler, Eve Shinbrot, , Mitchell J. Frederick

This study clarifies that NOTCH1 acts as a tumor suppressor in head and neck cancer, reducing cancer stem cells and improving prognosis, despite conflicting prior reports.

JCI Insight · Apr 16, 2026Peer-reviewedCancer Biology

Bypassing cisplatin resistance in Nrf2 hyperactivated head and neck cancer through effective PI3Kinase targeting

Pedram Yadollahi, Kelli A. McCord, Li Yang, Hussam Dayoub, Kalil Saab, Fonma Essien, Sean Hyslop, Emerald Kan, Kazi Mokim Ahmed, Parker R. Kirby, Vasanta Putluri, Chandrashekar R. Ambati, Karthik Reddy Kami Reddy, Patricia D. Castro, Heath Devin Skinner, , Vlad Constantin Sandulache

This paper identifies PI3K pathway activation in Nrf2-driven cisplatin-resistant HNSCC and shows that gedatolisib inhibits tumor growth and re-sensitizes cells to cisplatin.

British Journal of Cancer · Oct 6, 2025Peer-reviewedCancer Biology

Omics-Based Interaction Framework - a systems model to reveal molecular drivers of synergy

Jezreel Pantaleón García, Vikram V. Kulkarni, Tanner C. Reese, Shradha Wali, Saima J. Wase, Jiexin Zhang, Ratnakar Singh, Mauricio S. Caetano, Seyed Javad Moghaddam, Faye M. Johnson, Jing Wang, Yongxing Wang, Scott E. Evans

The paper introduces OBIF, a systems model that identifies molecular drivers of synergy by integrating statistical and biological interactions from omics data.

bioRxiv · Apr 16, 2020 · PreprintSystems Biology