Author

Honglei Li

Central South UniversityORCID 0000-0002-6085-0950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Organism:human· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Cheng WangiD· 1 shared Cheng ZhuiD· 1 shared Dong LiiD· 1 shared Fei GuoiD· 1 shared Feifei GuoiD· 1 shared Fuchu HeiD· 1 shared Gaomei Zhao· 1 shared Huarui Kang· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Cheng WangORCID

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2 papers

Recent·Most cited

BioinformaticseLifePeer-reviewedMar 13, 2025

Exploring the repository of de novo designed bifunctional antimicrobial peptides through deep learning

Ruihan Dong, Rongrong Liu, Ziyu Liu…·Cheng Zhu

This paper designs bifunctional antimicrobial peptides using deep learning, discovering 16 peptides with both antibacterial and antiviral activity, including two validated against drug-resistant bacteria and viruses.

4 citations

protein sequencedeep learning

𝕏 PostBluesky

BioinformaticsGenomics Proteomics & BioinformaticsPeer-reviewedMar 23, 2022

Exploration of target spaces in the human genome for protein and peptide drugs

Zhongyang Liu, Honglei Li, Zhaoyu Jin…·Dong Li

The paper systematically explores human genome target spaces for protein and peptide drugs, identifying distinct characteristics and developing genome-wide target estimation models for each.

4 citations

humanstatistical model

𝕏 PostBluesky