Enrichment of allelic editing outcomes by Prime Editing in iPS cells
Ryo Niwa, Tomoko Matsumoto, Alexander Y. Liu, Maki Kawato, Takayuki Kondo, Kayoko Tsukita, Peter Gee, Haruhisa Inoue, Thomas L. Maurissen, Knut Woltjen
This study compares Cas9 and Prime Editing (PE) in human iPS cells, showing PE's superior precision and demonstrating how sorting by PE expression affects allelic editing outcomes.
The CRISPR Journal · Oct 1, 2024Peer-reviewedBioengineering