Author

Thomas L. Maurissen

F. Hoffmann-La Roche AGORCID 0000-0002-9686-2400Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

A. Rizkallah· 1 shared Alex OdermattiD· 1 shared Angélique Augustin· 1 shared Ayako Nagahashi· 1 shared Barbara HöllbacheriD· 1 shared Cantas AleviD· 1 shared Chiara Zanini· 1 shared Christelle Zundel· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Rizkallah

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2 papers

Recent·Most cited

ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells

Luisa Bell, Shane Clerkin, Filiz Sila Rizalar, A. Rizkallah, Nadine Stokar‐Regenscheit, Xandor M. Spijkers, Nienke R. Wevers, Claire Simonneau, Angélique Augustin, Barbara Höllbacher, Lia D’Abate, Joanna Ficek, Kim Schneider, Désirée von Tell, Thomas L. Maurissen, , Roberto Villaseñor

The paper investigates how ApoE4 affects intracellular trafficking and iron homeostasis in human brain endothelial cells derived from iPSCs, showing altered endosomal organization and iron levels.

Stem Cell Reports · Aug 21, 2025Peer-reviewedCell Biology

Modeling the Human Segmentation Clock with Pluripotent Stem Cells

Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K. Saito, Ayako Nagahashi, Megumi Nishio, Long Zhe Guo, Shiro Ikegawa, Satoko Sakurai, Shunsuke Kihara, Thomas L. Maurissen, Michiko Nakamura, Tomoko Matsumoto, Hiroyuki Yoshitomi, , Cantas Alev

This study models the human segmentation clock using iPSC-derived presomitic mesoderm, identifying oscillatory genes and validating disease-related gene effects.

Nature · Apr 1, 2020Peer-reviewedDevelopmental Biology