Author

Feng Zhang

National Institutes of HealthORCID 0000-0002-6103-1498Unclaimed ORCID profile · follow to get notified of new preprints

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Feng Zhang9 papers · Chinese Academy of Sciences

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Neuroscience· 1

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Approach:experimental assay· 1

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Andrés Jara-OsegueraiD· 1 shared Kenton Jon SwartziD· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperNeuroscience

Andrés Jara-OsegueraORCID

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1 paper

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NeuroscienceeLifePeer-reviewedJan 15, 2019

Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity

Feng Zhang, Kenton Jon Swartz, Andrés Jara-Oseguera

This study engineers RTx sensitivity in TRPV3 by mutating residues corresponding to the TRPV1 vanilloid site and shows that activation requires additional factors like pore mutations or co-agonists.

32 citations

experimental assay

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