Yuuki Imai

This study identifies AR-dependent Mybph repression as a mechanism contributing to skeletal muscle sexual dimorphism using ChIL-seq and an AirID-AR knock-in mouse.

This study shows that Dnmt1 regulates bone length by controlling energy metabolism in chondrocytes through DNA methylation and gene expression changes.

This study shows that aromatase in adipose tissue protects bone in male mice by regulating phosphate reabsorption via NaPi2 proteins.

This study shows that androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice, with effects seen in adult but not young or aged mice.

The paper constructs a single-cell atlas of transcribed cis-regulatory elements in the human genome, revealing gene regulation patterns and trait-gene relationships across cell populations.

This study shows that Uhrf1 is essential for the proliferation and differentiation of muscle satellite cells by maintaining DNA methylation patterns.