Atsushi Kuno

This study identifies altered thick ascending limb cells with UMOD retention as drivers of CKD using spatial proteomics and shows reducing UMOD retention attenuates CKD development.

The paper introduces Lectin-IMC to spatially validate disease-associated glyco-niches using multimodal glycoprotein analysis in a cardiomyopathy model.

The paper defines sex-specific glycoproteomes in mouse tissues using multi-omics integration, revealing distinct glycoform patterns and enzyme relationships across 19 tissues.

This study evaluates five glycoproteomics software tools for identifying rare sialic acid-containing glycopeptides, finding that each tool has unique strengths and limitations in detection accuracy and reliability.

LM-GlycoRepo Version 1.0 is a repository for mouse tissue glycome mapping data that supports FAIR principles and includes an embargo system and visualization tool.

The paper identifies site-specific glycan compositions of SARS-CoV-2 spike protein using mass spectrometry and lectin microarray, revealing key glycan structures relevant to vaccine design.