Author

Irfahan Kassam

Illumina (United States)ORCID 0000-0002-6150-5614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:GWAS summary statistics· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Jeremy F. McRaeiD· 2 shared Petko P. FizieviD· 2 shared Abhishek SharmaiD· 1 shared Alexander V. GuseviD· 1 shared Alexandr BoytsoviD· 1 shared Allan F. McRaeiD· 1 shared Andres MetspaluiD· 1 shared Caleb A. LareauiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenetics

Jeremy F. McRaeORCID

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3 papers

Recent·Most cited

GeneticsNaturePeer-reviewedFeb 25, 2026

Functional dissection of complex and molecular trait variants at single nucleotide resolution

Layla Siraj, Rodrigo I. Castro, Hannah B. Dewey…·Ryan Tewhey

This study functionally characterizes 221,412 trait-associated variants using MPRA in 5 cell types, identifying 12,025 regulatory variants and revealing widespread epistasis and non-TF mechanisms.

42 citationstop 1%

humanDNA methylation

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Genetic & Genomic MedicinemedRxivPreprintJan 12, 2024

PrimateAI-3D outperforms AlphaMissense in real-world cohorts

David A. Parry, Tom Bosc, Tobias Hamp…·Kyle Kai‐How Farh

The paper benchmarks PrimateAI-3D and AlphaMissense on real-world cohorts, finding PrimateAI-3D performs better in rare-disease and biobank settings.

5 citations

humanGWAS summary statistics

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GeneticsNature CommunicationsPeer-reviewedJul 8, 2019

The effect of X-linked dosage compensation on complex trait variation

Julia Sidorenko, Irfahan Kassam, Kathryn E. Kemper…·Peter M. Visscher

The paper examines how X-linked dosage compensation affects genetic variation in complex traits, finding more genetic variation in males than females for X-linked loci.

82 citationstop 4%

humanbulk RNA-seq

𝕏 PostBluesky