Author

John Lygeros

ETH ZurichORCID 0000-0002-6159-1962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:statistical model· 2 Organism:fungi (other)· 1 Research Focus:software / tool· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Marianna RapsomanikiiD· 2 shared Patroula NathanailidouiD· 2 shared Zoi LygerouiD· 2 shared Amelia PaineiD· 1 shared Eve TasiudiiD· 1 shared Jonas WindhageriD· 1 shared Manuel Ramírez GarrastachoiD· 1 shared María Rodríguez MartíneziD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSystems Biology

Marianna RapsomanikiORCID

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2 papers

Recent·Most cited

A stochastic hybrid model for DNA replication incorporating protein mobility dynamics

Jonas Windhager, Amelia Paine, Patroula Nathanailidou, Eve Tasiudi, María Rodríguez Martínez, John Lygeros, Zoi Lygerou, Marianna Rapsomaniki

The paper presents a stochastic hybrid model of DNA replication in fission yeast that incorporates protein mobility dynamics and experimental data to simulate full-genome duplication and replication timing.

bioRxiv · Oct 25, 2022 · PreprintSystems Biology

In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity

Marianna Rapsomaniki, Stella Maxouri, Patroula Nathanailidou, Manuel Ramírez Garrastacho, Nikolaos-Nikiforos Giakoumakis, Stavros L. Taraviras, John Lygeros, Zoi Lygerou

The paper presents a stochastic hybrid model of DNA re-replication in fission yeast, showing cell-to-cell heterogeneity and genome plasticity through simulations and experimental validation.

NAR Genomics and Bioinformatics · Jan 28, 2021Peer-reviewedSystems Biology