Eve Tasiudi

The paper constructs synthetic genotype networks of gene regulatory networks in E. coli to study robustness and evolvability in genotype-phenotype maps.

The paper presents a stochastic hybrid model of DNA replication in fission yeast that incorporates protein mobility dynamics and experimental data to simulate full-genome duplication and replication timing.

This paper designs and demonstrates CRISPRi-based synthetic gene circuits in E. coli, including an oscillator, bistable switch, and stripe pattern-forming IFFL, showing the potential of CRISPRi for dynamic and multistable circuit construction.