NeurosciencebioRxivPreprint
Behavioural and Physiological Signatures of Chronic Unpredictable Mild Stress Models in Mice
Ines Erkizia-Santamaría, Luna Fernández, Igor Horrillo…·Jorge Emilio Ortega
This study compares different CUMS protocols in mice, finding that increased stress intensity, frequency, and duration lead to more pronounced depressive and anxiety-like behaviors, adrenal hypertrophy, and reduced body weight gain.
DOI 10.64898/2025.11.30.691402