Author

Obinna Ukogu

University of WashingtonORCID 0000-0002-6170-9035Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Armita NourmohammadiD· 1 shared Grégoire Y Altan-BonnetiD· 1 shared Zachary MontagueiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperImmunology

Armita NourmohammadORCID

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1 paper

Recent·Most cited

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedApr 24, 2026

Design principles of the cytotoxic CD8+ T-cell response

Obinna Ukogu, Zachary Montague, Grégoire Y Altan-Bonnet, Armita Nourmohammad

This study identifies design principles of cytotoxic CD8+ T-cell responses by modeling them as feedback-controlled programs, revealing trade-offs between infection clearance and immunopathology, and suggesting strategies for improving T-cell therapies.

DOI 10.1073/pnas.2528202123

mousestatistical model

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