Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewed
Stromal cells modulate innate immune cell phenotype and function in colorectal cancer via the Sialic acid/Siglec axis
Aoise O’Neill, Norashikin Zakaria, Hannah Egan…·Aideen E. Ryan
This study shows stromal cell sialylation via the Sialic acid/Siglec axis suppresses innate immune cell function in CRC, and targeting this pathway restores immune activity.
14 citationstop 4%