Luiz Mário Janini

Enlarging viral mutation estimation: a view from the distribution of mutation rates

This paper introduces a method to estimate mutation rates as a distribution rather than a single number, using sequencing data from a single viral replication cycle.

Genotype-Resolved Interaction Landscape of the Dengue Envelope Glycoprotein with Host Cellular Proteins: Structural Dynamics, Thermodynamic Cooperativity, and Binding Specificity

This study identifies four recurrent dengue envelope protein interaction architectures using computational methods and suggests viral stability depends on local network context.

Oncogenic HPV types identified in Paleolithic and Chalcolithic human genome sequencing data from Ust'-Ishim and Ötzi

The paper detects HPV16 in ancient human genomes from Ust'-Ishim and Ötzi, showing its presence in modern humans during the Upper Paleolithic.

Direct RNA sequencing reveals SARS-CoV-2 m6A sites and possible differential DRACH motif methylation among variants

The paper uses direct RNA sequencing to identify m6A sites and analyze DRACH motif methylation differences in SARS-CoV-2 variants.