Michael Schlierf

The paper uses magnetic tweezers with periodic forces to study multi-domain protein folding kinetics, showing how periodic forces can enhance intermediate states and enable quasi-equilibrium analysis.

The paper shows that antibiotic stress alters nucleoid structure and LexA localization in E. coli, with SOS activation and LexA exclusion depending on stress severity.

The paper shows that destabilizing the integron synaptic complex with peptides reduces bacterial adaptation to antibiotics without antimicrobial activity.

The paper identifies LpdA as the source of intrinsic autofluorescence in filamentous actinobacteria and shows its role in metabolic organization during growth.

The paper investigates how the mechanical stability of the integron synaptic complex affects recombination efficiency in bacteria, finding a strong correlation between stability and efficiency.

This study shows that thermal fluctuations drive conformational changes in the bacterial AAA+ protease FtsH, with ATP affecting state occupancy but not the number of states or timescale.