Author

Eilidh Sohini Mackenzie

Newcastle UniversityORCID 0000-0002-6214-0530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Arnaud BasléiD· 1 shared Kacper M. SendraiD· 1 shared Kevin John WaldroniD· 1 shared Rafał MazgajiD· 1 shared Thomas E. Kehl‐FieiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperEvolutionary Biology

Arnaud BasléORCID

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1 paper

Recent·Most cited

Evolutionary BiologybioRxivPreprintOct 23, 2025

A metalloenzyme's metal preference evolves through redox modulation driven by the cofactor's secondary coordination sphere

Eilidh Sohini Mackenzie, Kacper M. Sendra, Arnaud Baslé…·Kevin John Waldron

This study investigates how metal preference in SodFM enzymes evolves through redox modulation by the secondary coordination sphere, revealing a link between oxidation state and catalytic metal preference.

DOI 10.1101/2025.10.23.684290

protein structurestatistical model

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