Kevin John Waldron

Zinc preserves translational proteostasis to counteract aging and proteotoxicity in Caenorhabditis elegans

This study shows that zinc supplementation in aged C. elegans improves healthspan and protects against proteotoxicity by preserving translational proteostasis.

A Zur-dependent regulatory RNA involved in maintaining zinc homeostasis in Staphylococcus aureus

This study identifies two sRNAs in Staphylococcus aureus that regulate zinc homeostasis, showing their role in Zn-sparing responses and adaptation to metal limitation.

An engineered biofactory for efficient production of diverse recombinant superoxide dismutase isozymes loaded with specific metal ions for biochemical characterisation

This paper describes an engineered E. coli strain that produces recombinant superoxide dismutase isozymes with controlled metal loading for biochemical analysis.

Microaerobic Copper Stress Redirects Pyruvate Metabolism and Reveals a CopL-linked Nitrogen Response in Staphylococcus aureus.

This study shows that microaerobic copper stress in S. aureus redirects pyruvate metabolism and activates a CopL-linked nitrogen response, enhancing bacterial fitness in host environments.

A closely related pair of superoxide dismutase isozymes from Staphylococcus aureus show distinct stabilities and proton-exchange dynamics

This study compares the structural stability and proton-exchange dynamics of two closely related superoxide dismutase isozymes in Staphylococcus aureus, showing that the neofunctionalised camSOD is more stable than the ancestral MnSOD.

A metalloenzyme's metal preference evolves through redox modulation driven by the cofactor's secondary coordination sphere

This study investigates how metal preference in SodFM enzymes evolves through redox modulation by the secondary coordination sphere, revealing a link between oxidation state and catalytic metal preference.

The gonococcal vaccine candidate antigen NGO1701 is a N. gonorrhoeae periplasmic copper storage protein

This paper identifies NGO1701 as a copper storage protein in N. gonorrhoeae, showing its role in copper homeostasis and its potential as a vaccine target.