Kostiantyn Dreval

LCR-modules provides a flexible, automated suite of workflows for cancer genome analysis, supporting diverse sequencing types and enabling reproducible, scalable analysis of over 10,800 samples.

This paper identifies Mann-type DLBCL as a subtype of GCB-DLBCL characterized by oligomannose-type glycans in CDR-located AGS, associated with poor prognosis and distinct gene expression patterns.

The paper reanalyzes Reddy et al.'s 2017 DLBCL study, revealing discrepancies in mutation detection and outcome associations that render their findings non-replicable.