Benjamin Sale

This paper identifies Mann-type DLBCL as a subtype of GCB-DLBCL characterized by oligomannose-type glycans in CDR-located AGS, associated with poor prognosis and distinct gene expression patterns.

The paper introduces a protocol for extracting and characterizing full-length tumor immunoglobulin transcripts from RNA-seq data, enabling analysis of their sequences and potential clinical applications.

This study identifies mutations in the IgG heavy chain in follicular lymphoma and EZB DLBCL that enhance BCR signalling and oncogenicity by disrupting the IgG intracellular tail.