Emilia G. Entcheva

This paper demonstrates the use of optogenetic and sonogenetic biological actuators to pace unmodified cardiac tissue with high spatial precision and rapid integration.

The paper compares transcriptomes of HDACs, TFs, and ion channels in hiPSC-CMs and adult human heart to identify regulatory relationships and cardiotoxicity implications of HDAC inhibitors.

The paper uses optogenetic stimulation and computational models to analyze phase resetting in human iPSC-derived cardiomyocytes, showing how it explains cardiac arrhythmias and offers strategies to prevent them.

This study uses high-throughput pericellular oxygen measurements and computational modeling to assess how adrenergic drugs affect human iPSC-derived cardiomyocytes.

This study investigates oxygen dynamics in cardiac cells using experiments and modeling to optimize HT platforms for cardiac research.

A Halbach array modulates excitation wave speed in human cardiac cell assemblies with magnetic nanoparticles, increasing conduction velocity by up to 25% when aligned with the wave direction.

The paper shows that Zim3, used as a CRISPRi effector without guide RNAs, upregulates cardiac ion channel genes in iPSC-CMs, leading to a more mature phenotype.