Author

Niek de Vries

Amsterdam UMC Location University of AmsterdamORCID 0000-0002-6257-8604Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Akari SuzukiiD· 1 shared Akira Murasawa· 1 shared Aldo JongejaniD· 1 shared Alex J. MacGregoriD· 1 shared Anne C BartoniD· 1 shared Antoine H. C. van KampeniD· 1 shared Atsushi KumanogohiD· 1 shared Barbera D. C. van SchaikiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Akari SuzukiORCID

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2 papers

Recent·Most cited

AbSolution: interactive exploration of sequence-derived features in AIRR-seq repertoires

Rodrigo García-Valiente, Charisios Triantafyllou, Barbera D. C. van Schaik, Aldo Jongejan, Sabrina Pollastro, Dornatien Chuo Anang, Jeroen E. J. Guikema, Niek de Vries, Huub C. J. Hoefsloot, Antoine H. C. van Kampen

AbSolution enables integrated analysis of sequence-derived features in immune repertoires across datasets and conditions.

bioRxiv · May 22, 2026 · PreprintBioinformatics

Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis

Kazuyoshi Ishigaki, Saori Sakaue, Chikashi C. Terao, Yang Luo, Kyuto Sonehara, Kensuke Yamaguchi, Tiffany Amariuta, Chun Lai Too, Vincent A. Laufer, Ian C. Scott, Sébastien Viatte, Meiko Takahashi, Koichiro Ohmura, Akira Murasawa, Motomu Hashimoto, , Soumya Raychaudhuri

This study conducts a trans-ancestry GWAS of rheumatoid arthritis, identifying 124 loci, 34 novel, and shows improved polygenic risk score performance across populations.

medRxiv · Dec 1, 2021 · PreprintGenetic & Genomic Medicine