Author

Jan Paul Bebelman

Vrije Universiteit AmsterdamORCID 0000-0002-6264-2004Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Brian F. VolkmaniD· 1 shared Caitrin CruddeniD· 1 shared Carsten HoffmanniD· 1 shared Chérine BecharaiD· 1 shared Christopher T. SchaferiD· 1 shared Claudia V. Perez AlmeriaiD· 1 shared Julia DrubeiD· 1 shared Lejla Musli· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Brian F. VolkmanORCID

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1 paper

Recent·Most cited

Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies

Claudia V. Perez Almeria, Omolade Otun, Roman R. Schlimgen, Thomas D Lamme, Lotte Di Niro, Caitrin Crudden, Jan Paul Bebelman, Noureldine Youssef, Lejla Musli, Shawn E. Jenjak, Vladimir Bobkov, Julia Drube, Carsten Hoffmann, Brian F. Volkman, Sébastien Granier, , Martine J. Smit

This study uses inverse agonistic nanobodies to reveal constitutive activity of ACKR3, showing it drives non-canonical signaling and basal cell motility, suggesting therapeutic potential.

Nature Communications · Dec 2, 2025Peer-reviewedBiochemistry