Author

Siyuan Kong

Agricultural Genomics Institute at ShenzhenORCID 0000-0002-6318-9299Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Yubo ZhangiD· 3 shared Qitong HuangiD· 2 shared Xiusheng ZhuiD· 2 shared Yanling PengiD· 2 shared Biao Deng· 1 shared Chao WangiD· 1 shared Danli LiuiD· 1 shared Dashuai KongiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersGenomics

Yubo ZhangORCID

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3 papers

Recent·Most cited

A single-cell genomic strategy for alternative transcript start sites identification

Yanling Peng, Qitong Huang, Danli Liu, Siyuan Kong, Rui Kamada, Keiko Ozato, Yubo Zhang, Jun Zhu

The paper introduces a single-cell genomic method to identify alternative TSSs in mouse cells and shows it is accurate and sensitive, revealing more TSSs than previous methods.

Biotechnology Journal · Mar 1, 2024Peer-reviewedGenomics

Genome-wide identification of silencers in human cells

Xiusheng Zhu, Chao Wang, Dashuai Kong, Jing Luo, Biao Deng, Yi Gu, Siyuan Kong, Lei Huang, Yuwen Liu, Yubo Zhang

The paper identifies silencer regions in three human cell lines using MPRAs, finding 739,434, 643,484, and 491,952 silencer regions with inhibitory activity and enriched inhibitory motifs.

bioRxiv · Jun 20, 2023 · PreprintGenomics

Enhancer-promoter association determines Sox2 transcription regulation in mouse pluripotent cells

Lei Huang, Qing Li, Qitong Huang, Siyuan Kong, Xiusheng Zhu, Yanling Peng, Yubo Zhang

The paper investigates how different enhancer-promoter associations influence Sox2 transcription in mouse embryonic stem cells, revealing distinct biological effects based on interaction type.

bioRxiv · Mar 28, 2019 · PreprintMolecular Biology