Qitong Huang

The paper introduces a single-cell genomic method to identify alternative TSSs in mouse cells and shows it is accurate and sensitive, revealing more TSSs than previous methods.

This study identifies specific distal enhancer-promoter associations that can reprogram MEF cells into iPS-like clones, demonstrating a method to generate pluripotent cells through 3D chromatin conformation.

The paper investigates how different enhancer-promoter associations influence Sox2 transcription in mouse embryonic stem cells, revealing distinct biological effects based on interaction type.