Author

Hirotaka Ata

Mayo ClinicORCID 0000-0003-0027-205XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:zebrafish· 4 Research Focus:gene regulatory network inference· 3 Assay:CRISPR screen· 2 Assay:DNA methylation· 2 Organism:human· 2 Research Focus:variant calling· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Karl J. ClarkiD· 4 shared Stephen Carl EkkeriD· 4 shared Gabriel Martínez‐GálveziD· 2 shared Jarryd M. CampbelliD· 2 shared Xiaolei XuiD· 2 shared Alex Richard CookiD· 1 shared Alexey V. DvornikoviD· 1 shared Alvin C. H. MaiD· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersMolecular Biology

Karl J. ClarkORCID

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4 papers

Recent·Most cited

Molecular BiologyGenesPeer-reviewedJul 23, 2022

A primer genetic toolkit for exploring mitochondrial biology and disease using zebrafish

Ankit Sabharwal, Jarryd M. Campbell, Tanya L. Schwab…·Stephen Carl Ekker

The paper presents a collection of zebrafish genetic mutants for studying mitochondrial biology and disease.

15 citations

zebrafishexperimental assay

𝕏 PostBluesky

GeneticsbioRxivPreprintMay 28, 2021

Chimeric RNA:DNA Donorguide Improves HDR in vitro and in vivo

Brandon W. Simone, Han B. Lee, Camden L. Daby…·Stephen Carl Ekker

This paper introduces a Donorguide technology that improves HDR efficiency and precision by fusing an ssDNA template to tracrRNA, showing enhanced results in vitro and in vivo.

3 citations

𝕏 PostBluesky

Molecular BiologybioRxivPreprintApr 16, 2018

Toward Precision Molecular Surgery: Robust, Selective Induction of Microhomology-mediated End Joining in vivo

Hirotaka Ata, Thomas L. Ekstrom, Gabriel Martínez‐Gálvez…·Stephen Carl Ekker

This paper demonstrates that inducing Microhomology-mediated End Joining (MMEJ) in vivo can generate highly homogeneous mutant alleles, with a novel algorithm provided for predicting MMEJ-inducing sites.

1 citation

zebrafishCRISPR screen

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Molecular BiologybioRxivPreprintMar 22, 2018

Engineering targeted deletions in the mitochondrial genome

Jarryd M. Campbell, Ester Perales‐Clemente, Hirotaka Ata…·Stephen Carl Ekker

This paper introduces a method to engineer precise deletions in the mitochondrial genome using TALE proteins in zebrafish and human cells.

6 citations

𝕏 PostBluesky