Claudia Haferlach

The paper introduces ALLCatchR2, a machine learning classifier that identifies 20 T-ALL subtypes across multiple cohorts and age groups with high accuracy.

IntegrateALL is an RNA-seq pipeline that integrates expression-based subtyping, gene fusion detection, and virtual karyotyping to classify B-ALL with high accuracy.

This study identifies how developmental maturity and fusion partner influence treatment response in KMT2A-rearranged B-ALL across all ages.

This study shows MECOM represses myeloid differentiation by inhibiting CEBPA, and its overexpression in AML reduces CEBPA levels, maintaining stem cell state.

The paper investigates two STAT5B mutations in T cell leukemias, showing one causes gain-of-function and the other loss-of-function, with distinct impacts on immune cell populations and transcriptional activity.