Author
AstraZeneca (Sweden)ORCID 0000-0002-6334-9520Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Songpu Xie, Qiangbing Yang, Nazma Ilahibaks…·Joost P. G. Sluijter
This paper introduces a platform for efficient protein delivery using extracellular vesicles engineered with biogenesis-inspired features, achieving functional gene editing in vitro and in vivo.
Fiona Shilliday, Miguel Gancedo-Rodrigo, Ginto George…·John E. Linley
The paper identifies a chemical inhibitor of eIF2B that activates the Integrated Stress Response by stabilizing an inhibitory complex with phosphorylated eIF2.
Fengling Li, Suzanne Z. Ackloo, C. H. Arrowsmith…·Matthieu Schapira
The paper evaluates computational hit-finding methods for targeting the WDR domain of LRRK2, a Parkinson's disease protein, finding that diverse strategies yielded weakly potent compounds.