Sven Peine

The paper identifies altered CD4 T-cell immune profiles in NSCLC patients with oligo-metastatic brain disease compared to poly-metastatic disease and healthy controls.

This study shows that red blood cells from cancer patients enhance tumour cell invasiveness and metastatic potential through gene and protein changes, suggesting PAK4 as a therapeutic target.

This study evaluates the effectiveness of TIL-derived CD8 T-cells in suppressing tumor recurrence in HBV-HCC patients through adoptive cell transfer and immune checkpoint inhibitor combination.

The paper shows that LC4 cells derived from HCV-related HCC replicate the transcriptomic features of the parental tumor, including immune suppression and metabolic changes.

This study identifies six iron transport proteins in Plasmodium falciparum using RNA-sequencing and functional assays, revealing a new model of iron homeostasis in the parasite.