Maura Dandri

Merkel cell polyomavirus infection and persistence modelled in skin organoids

This paper demonstrates that iPSC-derived skin organoids support MCPyV infection, persistence, and tumor development, providing a model to study viral interactions with the immune system and treatment strategies.

Accessing the specific capacity of TIL-derived CD8 T-cells to suppress tumor recurrence in resectable HBV-HCC patients

This study evaluates the effectiveness of TIL-derived CD8 T-cells in suppressing tumor recurrence in HBV-HCC patients through adoptive cell transfer and immune checkpoint inhibitor combination.

Ex-vivo expansion of patient-derived PBMCs preferentially results in effector memory T-cell proliferation with restored autologous efficiency in HBV-HCC

Patient-derived HCC cells recapitulating the transcriptomic landscape of primary HCV-related liver cancer

The paper shows that LC4 cells derived from HCV-related HCC replicate the transcriptomic features of the parental tumor, including immune suppression and metabolic changes.