Author

Mirela Bălan

Science for Life LaboratoryORCID 0000-0002-6367-8244Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Bartłomiej PorębskiiD· 1 shared Daniela Hühn· 1 shared Jordi Carreras PuigvertiD· 1 shared Louise Lidemalm· 1 shared Maria HäggbladiD· 1 shared Oleksandra SirozhiD· 1 shared Óscar Fernández-CapetilloiD· 1 shared Valeria ColicchiaiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Bartłomiej PorębskiORCID

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1 paper

Recent·Most cited

Chemical and genetic screens identify new regulators of tetracycline-inducible gene expression system in mammalian cells

Valeria Colicchia, Maria Häggblad, Oleksandra Sirozh, Bartłomiej Porębski, Mirela Bălan, Louise Lidemalm, Jordi Carreras Puigvert, Daniela Hühn, Óscar Fernández-Capetillo

The paper identifies chemical and genetic regulators of the tetracycline-inducible gene expression system in mammalian cells, showing that FDA-approved drugs and genetic modifiers inhibit the system rather than alleviate TDP-43 toxicity.

bioRxiv · Mar 16, 2022 · PreprintMolecular Biology