Author

Liane M. Miller

Philadelphia VA Medical CenterORCID 0000-0002-6370-1627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

Robert L. MauckiD· 2 shared Alexandra A. SilvermaniD· 1 shared Brett J. CroeniD· 1 shared Carla R. ScanzelloiD· 1 shared Dakota L. JonesiD· 1 shared Edward D. BonnevieiD· 1 shared Elisabeth A. LemmoniD· 1 shared Elizabeth R. BernsteiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPathology

Robert L. MauckORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintOct 14, 2026

Mechano-activated synovial cells instigate OA-like disease progression in the absence of joint injury

Elizabeth R. Bernstein, Georgios Kotsaris, Alexandra A. Silverman…·Robert L. Mauck

This study shows that altering synovial cell mechanotransduction drives OA-like disease without joint injury, with partial effects on symptoms versus structural damage.

DOI 10.64898/2026.10.06.756770

mousebulk RNA-seq

GenomicsActa BiomaterialiaPeer-reviewedOct 9, 2025

Rapid Restoration of Cell Phenotype and Matrix Forming Capacity Following Transient Nuclear Softening

Ryan C. Locke, Liane M. Miller, Elisabeth A. Lemmon…·Robert L. Mauck

This study shows that transient nuclear softening with TSA treatment enhances cell migration and matrix formation in porcine meniscal cells, with full restoration of transcriptional phenotype and function within 7 days.

2 citations

experimental assay