BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Multi-substrate specificity shaped the complex evolution of the aminotransferase family across the tree of life
Kaan Koper, Sang‐Woo Han, Ramani Bhupendra Kothadia…·Hiroshi A. Maeda
The paper traces the evolutionary history of aminotransferases across species, revealing their substrate promiscuity and how it shaped nitrogen metabolic networks.