BiochemistryJournal of the American Chemical SocietyPeer-reviewed
De Novo Design, Directed Evolution and Computational Study of Heme-Binding Helical Bundle Protein Catalysts for Biocatalytic Enantioselective Ge-H Insertion
Wei Huang, Gessica M. Adornato, Maggie Horst…·Yang Yang
This paper designs and evolves de novo helical bundle proteins to catalyze enantioselective Ge-H insertion, showing improved efficiency and selectivity through computational analysis and directed evolution.
11 citations