Developmental BiologybioRxivPreprint
In vivo Imaging β-cell Function Reveals Two Waves of β-cell Maturation
Jia Zhao, Weijian Zong, Yi Wu…·Yanmei Liu
This study uses in vivo imaging in zebrafish to show that β-cell maturation occurs in two waves, initiated by low glucose and boosted by increased glucose delivery, with calcineurin/NFAT activation playing a key role.