CTCF blocks anti-sense transcription initiation at divergent gene promoters
Jing Yuan Luan, Camille M. Syrett, Marit Willemijn Vermunt, Allison Coté, Jacob M. Tome, Haoyue Zhang, Anran Huang, Jennifer M. Luppino, Cheryl A. Keller, Belinda M. Giardine, Shiping Zhang, Margaret C. Dunagin, Zhe Zhang, Eric F. Joyce, John T. Lis, , Gerd A. Blobel
The paper shows CTCF suppresses antisense transcription at divergent promoters without affecting sense transcription, using a combination of genetic and molecular techniques.
bioRxiv · Oct 30, 2021 · PreprintMolecular Biology