Global detection of DNA repair outcomes induced by CRISPR-Cas9
Mengzhu Liu, Weiwei Zhang, Changchang Xin, Jianhang Yin, Yafang Shang, Ai Chen, Jiaxin Li, Fei‐Long Meng, Jiazhi Hu
The paper develops an in silico pipeline to analyze CRISPR-Cas9-induced DNA repair outcomes, identifying deleterious byproducts like large deletions and chromosomal translocations.
Nucleic Acids Research · Jul 27, 2021Peer-reviewedGenomics