Author
Peking University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Yuanyi Dai, Zuliayeti Abudujielili, Yunyi Ding…·Chenjian Li
Self-inactivating CRISPR targeting mutant huntingtin in HD mice achieved long-term rescue of neural pathology, motor deficits, weight loss and survival.
Jinchun Wu, Yang Liu, Zhengrong Zhangding…·Jiazhi Hu
This study shows that cohesin coordinates DNA replication initiation to maintain proper replication timing and genome integrity by affecting dormant origin firing and preventing DNA breaks and translocations.
Mengzhu Liu, Weiwei Zhang, Changchang Xin…·Jiazhi Hu
The paper develops an in silico pipeline to analyze CRISPR-Cas9-induced DNA repair outcomes, identifying deleterious byproducts like large deletions and chromosomal translocations.