Author

Changchang Xin

Peking UniversityORCID 0009-0001-3786-8781Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Organism:mouse· 2 Research Focus:variant calling· 2 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jianhang Yin· 2 shared Jiazhi HuiD· 2 shared Mengzhu LiuiD· 2 shared Ai CheniD· 1 shared Fei‐Long MengiD· 1 shared Jiasheng LiiD· 1 shared Jiaxin LiiD· 1 shared Jinchun WuiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Jianhang Yin

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 19, 2023

Transfer of mitochondrial DNA into the nuclear genome during gene editing

Jinchun Wu, Yang Liu, Liqiong Ou…·Jiazhi Hu

This study shows that genome editing can transfer mitochondrial DNA into the nuclear genome, and provides a solution using TREX1 or TREX2 exonucleases.

DOI 10.1101/2023.07.19.549443

humanmouse

𝕏 PostBluesky

GenomicsNucleic Acids ResearchPeer-reviewedJul 27, 2021

Global detection of DNA repair outcomes induced by CRISPR-Cas9

Mengzhu Liu, Weiwei Zhang, Changchang Xin…·Jiazhi Hu

The paper develops an in silico pipeline to analyze CRISPR-Cas9-induced DNA repair outcomes, identifying deleterious byproducts like large deletions and chromosomal translocations.

109 citationstop 2%

humanmouse

𝕏 PostBluesky