BiochemistrybioRxivPreprint
Fusion of a functional glutaredoxin to the radical-generating subunit of ribonucleotide reductase
Inna Rozman Grinberg, Daniel Lundin, Margareta Sahlin…·Britt-Marie Sjöberg
This paper demonstrates that a fused glutaredoxin domain in F. ignava NrdB functions as a reductant for RNR via both dithiol and monothiol mechanisms, and shows the ATP-cone's role in regulating enzyme activity through dATP binding.
DOI 10.1101/373563