Author

Jos C. S. Kleinjans

Maastricht UniversityORCID 0000-0002-6421-138XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1

Frequent Co-Authors

Bart P. F. RutteniD· 1 shared Christiaan H. VinkersiD· 1 shared Clara SnijdersiD· 1 shared Courtney A. MilleriD· 1 shared Danyel G. J. JenneniD· 1 shared Elbert GeuzeiD· 1 shared Eric H. G. J. M. VermetteniD· 1 shared Florian CaimentiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperNeuroscience

Bart P. F. RuttenORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 20, 2022

Quantifying the number of translatable transcripts through the use of OMICs involved in post-transcriptional regulation.

Juan Ochoteco Asensio, Jos C. S. Kleinjans, Florian Caiment

The paper develops a model to estimate translatable transcripts by incorporating miRNA and circRNA data, improving the correlation between transcriptome and proteome expression levels in a compound-exposed dataset.

1 citation

bulk RNA-seqproteomics

𝕏 PostBluesky

Systems BiologyToxicology LettersPeer-reviewedJul 3, 2021

Contextualization of causal regulatory networks from toxicogenomics data applied to drug-induced liver injury

Panuwat Trairatphisan, Terezinha Maria de Souza, Jos C. S. Kleinjans…·Julio Sáez-Rodríguez

The paper applies a causal network tool to toxicogenomics data to infer regulatory networks in drug-induced liver injury, identifying conserved pathways between rat and human models.

4 citations

rathuman

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NeuroscienceMolecular PsychiatryPeer-reviewedMay 29, 2019

microRNA regulation of persistent stress-enhanced memory

Stephanie E. Daws, Sarah Jamieson, Laurence de Nijs…·Courtney A. Miller

The paper identifies mir-135b-5p as a regulator of persistent stress-enhanced memory and a potential therapeutic target and biomarker for PTSD.

44 citationstop 3%

mousehuman

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