Elbert Geuze

This study investigates if pre-trauma memory contextualization predicts PTSD-like behavior in rats, finding a negative relationship only in a non-stress group.

This paper classifies PTSD vs. controls using MRI data from multiple sites, finding better performance when distinguishing PTSD from trauma-unexposed controls than trauma-exposed controls, and showing DVAE improves generalizability.

This paper introduces a computational method to improve the reliability of epigenetic clocks by using principal component analysis, showing reduced technical noise and better performance in longitudinal studies.

This study examines structural covariance networks in PTSD using a large multisite dataset, finding differences in centrality measures between PTSD and control groups, and highlighting sex-based and comorbid differences.

The paper performs a meta-analysis of DNA methylation data from military cohorts to identify CpG sites and regions associated with PTSD development.

The paper uses neuroimaging data to predict psychotherapy outcomes in PTSD, identifying specific resting-state networks that distinguish responders from non-responders.

This study identifies hippocampal subfield volume differences in PTSD and depression across 31 cohorts, finding depression has a stronger effect than PTSD, especially in CA1, with comorbid cases showing more pronounced changes.

The paper identifies shared disconnectivity patterns in central brain pathways across twelve psychiatric and neurological disorders using a meta-analytic connectome study.

This study identifies reduced fractional anisotropy in the tapetum region of the corpus callosum in PTSD patients using a large multi-cohort analysis of diffusion MRI data.

The paper identifies mir-135b-5p as a regulator of persistent stress-enhanced memory and a potential therapeutic target and biomarker for PTSD.

This study identifies ten novel methylation loci associated with PTSD through a meta-analysis of 1,896 cases and controls across ten cohorts, highlighting the AHRR locus and its link to kynurenine levels.

This study conducts the largest GWAS for PTSD, identifying 6 genome-wide significant loci in European and African ancestries and highlighting novel biological pathways.