Stasimon contributes to the loss of sensory synapses and motor neuron death in a mouse model of spinal muscular atrophy
Christian M. Simon, Meaghan Van Alstyne, Francesco Lotti, Elena Bianchetti, Sarah Tisdale, Daniel Martin Watterson, George Z. Mentis, Livio Pellizzoni
This study shows that Stasimon overexpression in SMA mice improves motor function by preventing synaptic loss and motor neuron death through mechanisms involving p53 regulation.
Cell Reports · Jan 1, 2019Peer-reviewedNeuroscience