Zfp503/Nlz2 is Required for RPE Differentiation and Optic Fissure Closure
Elangovan Boobalan, A. Thompson, Ramakrishna P. Alur, David M. McGaughey, Lijin Dong, Grace C. Shih, Emile R. Vieta-Ferrer, Ighovie F. Onojafe, Vijay K. Kalaskar, Gavin Arno, Andrew John Lotery, Bin Guan, Chelsea Bender, Omar Memon, Lauren Brinster, , Brian P. Brooks
The paper shows that Zfp503 is essential for RPE differentiation and optic fissure closure, with loss of function leading to uveal coloboma and altered gene expression in developing mouse eyes.
Investigative Ophthalmology & Visual Science · Nov 3, 2022Peer-reviewedDevelopmental Biology