Author

Vijay K. Kalaskar

National Institutes of HealthORCID 0000-0002-4311-4783Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Brian P. BrooksiD· 2 shared Ramakrishna P. Alur· 2 shared Tiziana Cogliati· 2 shared A. ThompsoniD· 1 shared Ala MoshiriiD· 1 shared Andrea MinellaiD· 1 shared Andrew John LoteryiD· 1 shared Antonio Jacobo LopeziD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPharmacology & Toxicology

Brian P. BrooksORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 13, 2025

Ampyrone (4-Aminoantipyrine) is a Direct Agonist of Human Tyrosinase and Potential Therapeutic for Oculocutaneous Albinism and Disorders of Hypopigmentation.

Monika B. Dolinska, Yuhong Wang, Nathan P. Coussens…·Brian P. Brooks

The paper identifies ampyrone as a direct activator of human tyrosinase, showing increased catalytic activity and melanin synthesis in melanocytes and skin cultures, suggesting potential therapeutic use for hypopigmentation disorders.

1 citation

humanexperimental assay

𝕏 PostBluesky

Developmental BiologyInvestigative Ophthalmology & Visual SciencePeer-reviewedNov 3, 2022

Zfp503/Nlz2 is Required for RPE Differentiation and Optic Fissure Closure

Elangovan Boobalan, A. Thompson, Ramakrishna P. Alur…·Brian P. Brooks

The paper shows that Zfp503 is essential for RPE differentiation and optic fissure closure, with loss of function leading to uveal coloboma and altered gene expression in developing mouse eyes.

11 citations

mousebulk RNA-seq

𝕏 PostBluesky